In vivo, in conscious swine a model with GH axis pharmacology closely reflective of human GH secretion ipamorelin produced an ED50 of 2.3 0.03 nmol/kg and an Emax of 65 0.2 ng GH/mL plasma, comparable to GHRP-6 (ED50 3.9 1.4 nmol/kg, Emax 74 7 ng/mL) but with substantially superior selectivity
Retrieved 25 January 2025
Animal data confirms increased nitrogen retention with LR3 IGF-1 (Tomas et al., 1993), but most of the visible scale movement during a 10-day cycle reflects increased intracellular water and glycogen rather than new contractile protein
Whole blood samples were assayed for standard cell blood counts with percentage differentials [i.e., hemoglobin, hematocrit, platelet, red blood cell counts, mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), red blood cell distribution width (RDW), white blood cell counts (neutrophils, lymphocytes, monocytes, eosinophils, basophils)